Marcelo G. Kazanietz

University of Pennsylvania, Philadelphia, PA, United States 
Oncology, Cell Biology, Medicine and Surgery
"Marcelo Kazanietz"


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Francheska Colon-Gonzalez grad student 2009 Penn
Hongbin Wang grad student 2010 Penn
Mahlet B. Abera grad student 2014 Penn
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Garg R, Cooke M, Benavides F, et al. (2020) PKC epsilon is required for KRAS-driven lung tumorigenesis. Cancer Research
Casado-Medrano V, Barrio-Real L, Gutiérrez-Miranda L, et al. (2019) Identification of a truncated β1-chimaerin variant that inactivates nuclear Rac1. The Journal of Biological Chemistry
Llorens MC, Rossi FA, García IA, et al. (2019) PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1. Frontiers in Oncology. 9: 1323
Casado-Medrano V, Barrio-Real L, Wang A, et al. (2019) Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells. Oncogene
Casado-Medrano V, Baker MJ, Lopez-Haber C, et al. (2018) The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic. Biochemical Society Transactions
Barrio-Real L, Lopez-Haber C, Casado-Medrano V, et al. (2018) P-Rex1 is dispensable for Erk activation and mitogenesis in breast cancer. Oncotarget. 9: 28612-28624
Garg R, Blando JM, Perez CJ, et al. (2018) COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer. Oncogene
Cooke M, Zhou X, Casado-Medrano V, et al. (2018) Characterization of AJH-836, a DAG-lactone with selectivity for novel PKC isozymes. The Journal of Biological Chemistry
Bessa C, Soares J, Raimundo L, et al. (2018) Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy. Cell Death & Disease. 9: 23
Kazanietz MG, Caloca MJ. (2017) The Rac GTPase in cancer: from old concepts to new paradigms. Cancer Research
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