Steven B. McMahon

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
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"Steven McMahon"

Children

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Jagruti H. Patel grad student 2006 Penn
Stephen M. Sykes grad student 2007 Penn
Hestia S. Mellert grad student 2011 Penn
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Publications

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Stanek TJ, Gennaro VJ, Tracewell MA, et al. (2021) The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22. The Embo Journal. e102509
Farkas M, McMahon S. (2021) Unlocking p53 response elements: DNA shape is the key. Molecular & Cellular Oncology. 8: 1905489
Farkas M, Hashimoto H, Bi Y, et al. (2021) Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates. Nature Communications. 12: 484
McCann JJ, Vasilevskaya IA, Poudel Neupane N, et al. (2019) USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair. Cancer Research
Farkas M, McMahon SB. (2019) Rapid Detection of p53 Acetylation Status in Response to Cellular Stress Signaling. Methods in Molecular Biology (Clifton, N.J.). 1983: 255-262
Barta JA, Pauley K, Kossenkov AV, et al. (2019) The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer. Carcinogenesis
Gennaro VJ, Wedegaertner H, McMahon SB. (2019) Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC. Bmc Cancer. 19: 258
Barta JA, McMahon SB. (2018) Lung-enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-specific Gain of Oncogenic Function. Molecular Cancer Research : McR
Gennaro VJ, Stanek TJ, Peck AR, et al. (2018) Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. Proceedings of the National Academy of Sciences of the United States of America
Barta JA, McMahon SB. (2018) Abstract A25: Urokinase plasminogen activator expression is regulated by p53 harboring the lung cancer-specific mutation V157F Clinical Cancer Research. 24
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