Tomas A. Prolla

University of Wisconsin, Madison, Madison, WI 
Genetics, Animal Physiology Biology, Molecular Biology
"Tomas Prolla"


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Cheol-Koo Lee grad student 2003 UW Madison
Sang-Kyu Park grad student 2006 UW Madison
Radhika Puttagunta grad student 2006 UW Madison
Patrick C. Bradshaw post-doc 2005-2007 UW Madison (Physics Tree)
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Barger JL, Vann JM, Cray NL, et al. (2017) Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. Aging Cell
Someya S, Kujoth GC, Kim MJ, et al. (2017) Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice. Plos One. 12: e0171159
Han C, Linser P, Park HJ, et al. (2016) Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice. Neurobiology of Aging. 43: 58-71
Orogo AM, Gonzalez ER, Kubli DA, et al. (2015) Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. The Journal of Biological Chemistry
Dittenhafer-Reed KE, Richards AL, Fan J, et al. (2015) SIRT3 mediates multi-tissue coupling for metabolic fuel switching. Cell Metabolism. 21: 637-46
Barger JL, Anderson RM, Newton MA, et al. (2015) A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3. Plos One. 10: e0120738
Li-Harms X, Milasta S, Lynch J, et al. (2015) Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice. Blood. 125: 162-74
Dai Y, Clark J, Zheng K, et al. (2014) Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicology and Teratology. 46: 62-7
Hsu KT, Yu XM, Audhya AW, et al. (2014) Novel approaches in anaplastic thyroid cancer therapy. The Oncologist. 19: 1148-55
Kukreja L, Kujoth GC, Prolla TA, et al. (2014) Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease. Molecular Neurodegeneration. 9: 16
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