Oliver G. McDonald, Ph.D.

2006 University of Virginia, Charlottesville, VA 
Molecular Biology
"Oliver McDonald"


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Gary K. Owens grad student 2006 UVA
 (Epigenetic regulation of smooth muscle differentiation.)
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Hansen KD, Timp W, Bravo HC, et al. (2011) Increased methylation variation in epigenetic domains across cancer types. Nature Genetics. 43: 768-75
Hastings NE, Simmers MB, McDonald OG, et al. (2007) Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33
McDonald OG, Owens GK. (2007) Programming smooth muscle plasticity with chromatin dynamics. Circulation Research. 100: 1428-41
Gan Q, Yoshida T, McDonald OG, et al. (2007) Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 2-9
Davis CA, Haberland M, Arnold MA, et al. (2006) PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Molecular and Cellular Biology. 26: 2626-36
McDonald OG, Wamhoff BR, Hoofnagle MH, et al. (2006) Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. The Journal of Clinical Investigation. 116: 36-48
Hendrix JA, Wamhoff BR, McDonald OG, et al. (2005) 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo. The Journal of Clinical Investigation. 115: 418-27
Liu Y, Sinha S, McDonald OG, et al. (2005) Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. The Journal of Biological Chemistry. 280: 9719-27
Wamhoff BR, Hoofnagle MH, Burns A, et al. (2004) A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis. Circulation Research. 95: 981-8
Wamhoff BR, Bowles DK, McDonald OG, et al. (2004) L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism. Circulation Research. 95: 406-14
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