Qiong Gan, Ph.D.

2007 University of Virginia, Charlottesville, VA 
Molecular Biology
"Qiong Gan"


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Gary K. Owens grad student 2007 UVA
 (Smooth muscle cells and myofibroblasts employ distinct transcriptional mechanisms for smooth muscle alpha-actin expression.)
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Gan Q, Thiébaud P, Thézé N, et al. (2011) WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. The Journal of Biological Chemistry. 286: 21853-64
Jin L, Gan Q, Zieba BJ, et al. (2010) The actin associated protein palladin is important for the early smooth muscle cell differentiation. Plos One. 5: e12823
Yoshida T, Gan Q, Franke AS, et al. (2010) Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. The Journal of Biological Chemistry. 285: 21175-84
Deaton RA, Gan Q, Owens GK. (2009) Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1027-37
Cherepanova OA, Pidkovka NA, Sarmento OF, et al. (2009) Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration. Circulation Research. 104: 609-18
Yoshida T, Gan Q, Owens GK. (2008) Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids. American Journal of Physiology. Cell Physiology. 295: C1175-82
Gan Q, Yoshida T, Li J, et al. (2007) Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression. Circulation Research. 101: 883-92
Gan Q, Yoshida T, McDonald OG, et al. (2007) Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells (Dayton, Ohio). 25: 2-9
Yoshida T, Gan Q, Shang Y, et al. (2007) Platelet-derived growth factor-BB represses smooth muscle cell marker genes via changes in binding of MKL factors and histone deacetylases to their promoters. American Journal of Physiology. Cell Physiology. 292: C886-95
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