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David K. Clawson, Ph.D.

Affiliations: 
2000 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology
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"David Clawson"
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Jean A. Hamilton-Steinrauf grad student 2000 Indiana University
 (The three dimensional structure of the Harvey -Ras G12V V45E mutant complexed with guanosine diphosphate and the nonhydrolyzable analog of guanosine triphosphate, guanylylimido diphosphate.)

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Henry JR, Kaufman MD, Peng SB, et al. (2015) Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells. Journal of Medicinal Chemistry. 58: 4165-79
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