Matthew L. Bettini, Ph.D.

Affiliations: 
2008 Emory University, Atlanta, GA 
Area:
Immunology
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"Matthew Bettini"

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Gilbert J. Kersh grad student 2008 Emory
 (The role of dual specificity phosphatases in thymopoiesis and T cell activation.)
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Publications

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Jing Y, Kong Y, Allard D, et al. (2023) Increased TCR signaling in regulatory T cells is disengaged from TCR affinity. Biorxiv : the Preprint Server For Biology
Szwarc MM, Hai L, Maurya VK, et al. (2022) Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine. 160: 156022
Majumdar S, Lin Y, Bettini ML. (2022) Host-microbiota interactions shaping T-cell response and tolerance in type 1 diabetes. Frontiers in Immunology. 13: 974178
Lin Y, Perovanovic J, Kong Y, et al. (2022) Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes. Diabetes
Kong Y, Jing Y, Allard D, et al. (2022) A dormant T-cell population with autoimmune potential exhibits low self-reactivity and infiltrates islets in type 1 diabetes. European Journal of Immunology
Jing Y, Kong Y, McGinty J, et al. (2022) TCR/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Post-translationally Modified GAD65 Epitope. Diabetes
Zegarra-Ruiz DF, Kim DV, Norwood K, et al. (2021) Thymic development of gut-microbiota-specific T cells. Nature
Ramstead AG, Wallace JA, Lee SH, et al. (2020) Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development. Cell Reports. 30: 2889-2899.e6
Jing Y, Kong Y, Mcginty J, et al. (2020) 287-OR: TCR/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope Diabetes. 69
Bettini M, Scavuzzo MA, Liu B, et al. (2019) A Critical Insulin TCR Contact Residue Selects High Affinity and Pathogenic Insulin Specific T Cells. Diabetes
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