Shashi Madhavan, Ph.D.

Affiliations: 
2007 Ohio State University, Columbus, Columbus, OH 
Area:
Cell Biology, Molecular Biology
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"Shashi Madhavan"

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Sudha Agarwal grad student 2007 Ohio State
 (Biomechanical signals mediate cellular mechano -transduction and gene regulation.)
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Publications

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Perera PM, Wypasek E, Madhavan S, et al. (2010) Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes. Arthritis Research & Therapy. 12: R106
Agarwal S, Perera P, Madhavan S, et al. (2009) 272 INTEGRIN LINKED KINASE-MEDIATED RAS ACTIVATION IS REQUIRED FOR MECHANOTRANSDUCTION-INDUCED PROLIFERATION AND DIFFERENTIATION IN ARTICULAR CHONDROCYTES Osteoarthritis and Cartilage. 17: S147-S148
Knobloch TJ, Madhavan S, Nam J, et al. (2008) Regulation of chondrocytic gene expression by biomechanical signals. Critical Reviews in Eukaryotic Gene Expression. 18: 139-50
Madhavan S, Anghelina M, Sjostrom D, et al. (2007) Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 6246-54
Dossumbekova A, Anghelina M, Madhavan S, et al. (2007) Biomechanical signals inhibit IKK activity to attenuate NF-kappaB transcription activity in inflamed chondrocytes. Arthritis and Rheumatism. 56: 3284-96
Madhavan S, Nam J, Rath B, et al. (2007) 158 SUSTAINED EFFECTS OF BIOMECHANICAL SIGNALS ARE MEDIATED VIA PROLONGED INHIBITION OF I-KAPPA B KINASE ACTIVATION IN ARTICULAR CHONDROCYTES Osteoarthritis and Cartilage. 15: C95-C96
Agarwal S, Madhavan S, Anghelina M, et al. (2007) 53 BIOMECHANICAL SIGNALS BLOCK IKK ACTIVATION TO INHIBIT NF-κB-MEDIATED PROINFLAMMATORY GENE TRANSCRIPTION IN ARTICULAR CHONDROCYTES Osteoarthritis and Cartilage. 15: C43
Madhavan S, Anghelina M, Rath-Deschner B, et al. (2006) Biomechanical signals exert sustained attenuation of proinflammatory gene induction in articular chondrocytes. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 14: 1023-32
Ferretti M, Madhavan S, Deschner J, et al. (2006) Dynamic biophysical strain modulates proinflammatory gene induction in meniscal fibrochondrocytes. American Journal of Physiology. Cell Physiology. 290: C1610-5
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