Katherine L. Cook, Ph.D.

Affiliations: 
2010 Wake Forest University, Winston-Salem, NC, United States 
Area:
Molecular Biology
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"Katherine Cook"

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E Ann Tallant grad student 2010 Wake Forest
 (Angiotensin-(1-7): A peptide hormone inhibitor for the treatment of breast cancer targeting the tumor microenvironment.)
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Publications

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Ramirez MU, Hernandez SR, Soto-Pantoja DR, et al. (2019) Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response. International Journal of Molecular Sciences. 21
Chiba A, Bawaneh A, Velazquez C, et al. (2019) Neoadjuvant chemotherapy shifts breast tumor microbiota populations to regulate drug responsiveness and the development of metastasis. Molecular Cancer Research : McR
Stirling ER, Cook KL, Roberts DD, et al. (2019) Metabolomic Analysis Reveals Unique Biochemical Signatures Associated with Protection from Radiation Induced Lung Injury by Lack of Receptor Gene Expression. Metabolites. 9
Wärri A, Cook KL, Hu R, et al. (2018) Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes. Cell Death Discovery. 5: 40
Shively CA, Register TC, Appt SE, et al. (2018) Consumption of Mediterranean versus Western Diet Leads to Distinct Mammary Gland Microbiome Populations. Cell Reports. 25: 47-56.e3
Feliz-Mosquea YR, Christensen AA, Wilson AS, et al. (2018) Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy. Breast Cancer Research and Treatment
Abunimer AN, Mohammed H, Cook KL, et al. (2018) Mitochondrial autophagosomes as a mechanism of drug resistance in breast carcinoma. Ultrastructural Pathology. 1-11
Soto-Pantoja DR, Wilson AS, Clear KY, et al. (2017) Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness. Oncotarget. 8: 80545-80559
Cook KL, Soto-Pantoja DR. (2017) "UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses. Biomarker Research. 5: 26
Cook KL, Soto-Pantoja DR, Clarke PA, et al. (2016) Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer. Cancer Research. 76: 5657-5670
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