Jonathon N. Winnay, Ph.D.

Affiliations: 
2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular Biology
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"Jonathon Winnay"

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Gary D. Hammer grad student 2006 University of Michigan
 (ACTH -dependent regulation of steroidogenic enzyme gene transcription: An analysis of complex and dynamic events.)
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Publications

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Winnay JN, Solheim MH, Sakaguchi M, et al. (2020) Inhibition of the PI 3-kinase pathway disrupts the unfolded protein response and reduces sensitivity to ER stress-dependent apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Solheim MH, Winnay JN, Batista TM, et al. (2018) Mice Carrying a Dominant-Negative Human PI 3-Kinase Mutation are Protected From Obesity and Hepatic Steatosis But Not Diabetes. Diabetes
Solheim MH, Clermont AC, Winnay JN, et al. (2017) Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase. Investigative Ophthalmology & Visual Science. 58: 3100-3106
Cai W, Sakaguchi M, Kleinridders A, et al. (2017) Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nature Communications. 8: 14892
Thomou T, Mori MA, Dreyfuss JM, et al. (2017) Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature
Sakaguchi M, Fujisaka S, Cai W, et al. (2017) Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor. Cell Metabolism
Palsgaard J, Emanuelli B, Winnay JN, et al. (2016) Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5). The Journal of Biological Chemistry. 291: 16878
Softic S, Boucher J, Solheim MH, et al. (2016) Lipodystrophy Due to Adipose Tissue Specific Insulin Receptor Knockout Results in Progressive NAFLD. Diabetes
Winnay JN, Solheim MH, Dirice E, et al. (2016) PI3-kinase mutation linked to insulin and growth factor resistance in vivo. The Journal of Clinical Investigation
Winnay JN, Dirice E, Liew CW, et al. (2014) p85α deficiency protects β-cells from endoplasmic reticulum stress-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 1192-7
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