Yuxing Zhao, Ph.D.

Affiliations: 
2007 Duke University, Durham, NC 
Area:
Pharmacology
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"Yuxing Zhao"

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Jeffrey Rathmell grad student 2007 Duke
 (Regulation of cell death by glucose metabolism.)
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Publications

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Zhao Y, Pu D, Sun Y, et al. (2017) High glucose-induced defective thrombospondin-1 release from astrocytes via TLR9 activation contributes to the synaptic protein loss. Experimental Cell Research
Sun Y, Xiao Q, Luo C, et al. (2017) High-glucose induces tau hyperphosphorylation through activation of TLR9-P38MAPK pathway. Experimental Cell Research
Zhao Y, Scott NA, Fynch S, et al. (2015) Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes. Diabetologia. 58: 140-8
Klionsky DJ, Abdalla FC, Abeliovich H, et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544
Coloff JL, Mason EF, Altman BJ, et al. (2011) Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. The Journal of Biological Chemistry. 286: 5921-33
Mason EF, Zhao Y, Goraksha-Hicks P, et al. (2011) Abstract LB-261: Maintenance of aerobic glycolysis provides selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl through suppression of p53 activation Cancer Research. 71
Mason EF, Zhao Y, Goraksha-Hicks P, et al. (2010) Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl. Cancer Research. 70: 8066-76
Altman BJ, Wofford JA, Zhao Y, et al. (2009) Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. Molecular Biology of the Cell. 20: 1180-91
Zhao Y, Coloff JL, Ferguson EC, et al. (2008) Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation Journal of Biological Chemistry. 283: 36344-36353
Zhao Y, Wieman HL, Jacobs SR, et al. (2008) Chapter Twenty-Two Mechanisms and Methods in Glucose Metabolism and Cell Death Methods in Enzymology. 442: 439-457
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