Rajan Sah, Ph.D.

Affiliations: 
2003 University of Toronto, Toronto, ON, Canada 
Area:
Animal Physiology Biology, Molecular Biology
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"Rajan Sah"

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Peter H. Backx grad student 2003 University of Toronto
 (Role of the transient outward potassium current and action potential profile in cardiac excitation -contraction coupling, hypertrophy and failure.)
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Publications

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Grimes D, Johnson R, Pashos M, et al. (2020) ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense. Proceedings of the National Academy of Sciences of the United States of America
Zhou JJ, Luo Y, Chen SR, et al. (2020) LRRC8A-dependent volume-regulated anion channels contribute to ischemia-induced brain injury and glutamatergic input to hippocampal neurons. Experimental Neurology. 113391
Kang C, Xie L, Gunasekar SK, et al. (2018) SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia. Nature Communications. 9: 367
Abiria SA, Krapivinsky G, Sah R, et al. (2017) TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles. Proceedings of the National Academy of Sciences of the United States of America
Sah R, Mesirca P, Van den Boogert M, et al. (2013) Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proceedings of the National Academy of Sciences of the United States of America. 110: E3037-46
Sah R, Mesirca P, Mason X, et al. (2013) Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation. 128: 101-14
Sah R, Mesirca P, Mason X, et al. (2013) The Ion Channel-Kinase, TRPM7, is Required for Cardiac Automaticity Biophysical Journal. 104: 379a
Sah R, Bates-Withers C, Mason X, et al. (2012) Cardiac-Targeted TRPM7 Deletion Induces Heart Block and Cardiomyopathy via Disrupted Embryonic Ventricular Development Biophysical Journal. 102: 344a
Ramirez RJ, Sah R, Liu J, et al. (2011) Intracellular [Na(+)] modulates synergy between Na(+)/Ca (2+) exchanger and L-type Ca (2+) current in cardiac excitation-contraction coupling during action potentials. Basic Research in Cardiology. 106: 967-77
Bates-Withers C, Sah R, Clapham DE. (2011) TRPM7, the Mg(2+) inhibited channel and kinase. Advances in Experimental Medicine and Biology. 704: 173-83
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