Valerie S. LeBleu, Ph.D.
Affiliations: | 2009 | Harvard University, Cambridge, MA, United States |
Area:
Cell BiologyGoogle:
"Valerie LeBleu"Parents
Sign in to add mentor| Raghu Kalluri | grad student | 2009 | Harvard | |
| (The pathobiochemistry of Alport syndrome and mechanism of cell-based therapy.) | ||||
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Publications
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| LeBleu VS, Dai J, Tsutakawa S, et al. (2023) Identification of unique α4 chain structure and conserved antiangiogenic activity of α3NC1 type IV collagen in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists |
| Mahadevan KK, McAndrews KM, LeBleu VS, et al. (2023) Oncogenic Kras specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 T cells dependent manner. Biorxiv : the Preprint Server For Biology |
| Melo SA, Luecke LB, Kahlert C, et al. (2022) Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature |
| LeBleu VS. (2022) Plasticity Enables Cooperation among Heterogeneous Cancer Cell Populations to Support Metastatic Fitness. Cancer Research. 82: 1870-1871 |
| McAndrews KM, Chen Y, Darpolor JK, et al. (2022) Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL-6 Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discovery |
| McAndrews KM, Miyake T, Ehsanipour EA, et al. (2022) Dermal αSMA myofibroblasts orchestrate skin wound repair via β1 integrin and independent of type I collagen production. The Embo Journal. e109470 |
| El-Shennawy L, Hoffmann AD, Dashzeveg NK, et al. (2022) Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nature Communications. 13: 405 |
| Zhou X, Kurywchak P, Wolf-Dennen K, et al. (2021) Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. Molecular Therapy. Methods & Clinical Development. 22: 360-376 |
| McAndrews KM, Xiao F, Chronopoulos A, et al. (2021) Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras in pancreatic cancer. Life Science Alliance. 4 |
| McAndrews KM, Vázquez-Arreguín K, Kwak C, et al. (2021) αSMA fibroblasts suppress Lgr5 cancer stem cells and restrain colorectal cancer progression. Oncogene |