Winston Y. Lee, Ph.D.

Affiliations: 
2009 Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Immunology, Molecular Biology
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"Winston Lee"

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A Parkos grad student 2009 Emory
 (Structure function analysis of SIRPalpha-CD47 interactions.)
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Publications

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Fournier B, Andargachew R, Robin AZ, et al. (2012) Surfactant protein D (Sp-D) binds to membrane-proximal domain (D3) of signal regulatory protein α (SIRPα), a site distant from binding domain of CD47, while also binding to analogous region on signal regulatory protein β (SIRPβ). The Journal of Biological Chemistry. 287: 19386-98
Brazil JC, Lee WY, Kolegraff KN, et al. (2010) Neutrophil migration across intestinal epithelium: evidence for a role of CD44 in regulating detachment of migrating cells from the luminal surface. Journal of Immunology (Baltimore, Md. : 1950). 185: 7026-36
Lee WY, Weber DA, Laur O, et al. (2010) The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47. The Journal of Biological Chemistry. 285: 37953-63
Nava P, Koch S, Laukoetter MG, et al. (2010) Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity. 32: 392-402
Chin AC, Fournier B, Peatman EJ, et al. (2009) CD47 and TLR-2 cross-talk regulates neutrophil transmigration. Journal of Immunology (Baltimore, Md. : 1950). 183: 5957-63
Severson EA, Lee WY, Capaldo CT, et al. (2009) Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration. Molecular Biology of the Cell. 20: 1916-25
Zuckerman JD, Lee WY, DelGaudio JM, et al. (2008) Pathophysiology of nasal polyposis: the role of desmosomal junctions. American Journal of Rhinology. 22: 589-97
Chin AC, Lee WY, Nusrat A, et al. (2008) Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration. Journal of Immunology (Baltimore, Md. : 1950). 181: 5702-10
Babbin BA, Laukoetter MG, Nava P, et al. (2008) Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. Journal of Immunology (Baltimore, Md. : 1950). 181: 5035-44
Stefanidakis M, Newton G, Lee WY, et al. (2008) Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro. Blood. 112: 1280-9
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