Lubna Patrawala, Ph.D.

Affiliations: 
2007 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology
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"Lubna Patrawala"

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Dean G. Tang grad student 2007 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Stem -like cancer cells in human cell lines and xenografts: Identification and characterization.)
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Publications

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Liu C, Kelnar K, Liu B, et al. (2011) The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nature Medicine. 17: 211-5
Wiggins JF, Ruffino L, Kelnar K, et al. (2010) Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Research. 70: 5923-30
Takeshita F, Patrawala L, Osaki M, et al. (2010) Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 181-7
Li H, Jiang M, Honorio S, et al. (2009) Methodologies in assaying prostate cancer stem cells. Methods in Molecular Biology (Clifton, N.J.). 568: 85-138
Jeter CR, Badeaux M, Choy G, et al. (2009) Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells (Dayton, Ohio). 27: 993-1005
Bhatia B, Jiang M, Suraneni M, et al. (2008) Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. The Journal of Biological Chemistry. 283: 27957-72
Esquela-Kerscher A, Trang P, Wiggins JF, et al. (2008) The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle (Georgetown, Tex.). 7: 759-64
Bhatia B, Multani AS, Patrawala L, et al. (2008) Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. International Journal of Cancer. Journal International Du Cancer. 122: 1483-95
Patrawala L, Calhoun-Davis T, Schneider-Broussard R, et al. (2007) Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells. Cancer Research. 67: 6796-805
Tang DG, Patrawala L, Calhoun T, et al. (2007) Prostate cancer stem/progenitor cells: identification, characterization, and implications. Molecular Carcinogenesis. 46: 1-14
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