Josef D. Franke, Ph.D.

Affiliations: 
2005 Duke University, Durham, NC 
Area:
Cell Biology
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"Josef Franke"

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Daniel P. Kiehart grad student 2005 Duke
 (Studies on nonmuscle myosin-IIs: From subunit assembly to human disease; from contractility to cell sheet migration.)
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Publications

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Sampathkumar P, Kim SJ, Manglicmot D, et al. (2012) Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata. Proteins. 80: 2110-6
Fernandez-Martinez J, Phillips J, Sekedat MD, et al. (2012) Structure-function mapping of a heptameric module in the nuclear pore complex. The Journal of Cell Biology. 196: 419-34
Twist KA, Husnain SI, Franke JD, et al. (2011) A novel method for the production of in vivo-assembled, recombinant Escherichia coli RNA polymerase lacking the α C-terminal domain. Protein Science : a Publication of the Protein Society. 20: 986-95
Sampathkumar P, Gheyi T, Miller SA, et al. (2011) Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex. Proteins. 79: 1672-7
Franke JD. (2010) Approaches for using animal models to identify loci that genetically interact with human disease-causing point mutations. Methods in Molecular Biology (Clifton, N.J.). 634: 203-13
Franke JD, Montague RA, Kiehart DP. (2010) Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. Developmental Biology. 345: 117-32
Santarella-Mellwig R, Franke J, Jaedicke A, et al. (2010) The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins. Plos Biology. 8: e1000281
Franke JD, Montague RA, Rickoll WL, et al. (2007) An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character. Human Molecular Genetics. 16: 3160-73
Franke JD, Boury AL, Gerald NJ, et al. (2006) Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster. Cell Motility and the Cytoskeleton. 63: 604-22
Franke JD, Montague RA, Kiehart DP. (2005) Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. Current Biology : Cb. 15: 2208-21
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