Ryan J. Hoefen, Ph.D.

2005 University of Rochester, Rochester, NY 
"Ryan Hoefen"


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Bradford C. Berk grad student 2005 Rochester
 (Functional analysis of G protein-coupled receptor kinase interacting protein 1 (GIT1).)
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Pang J, Hoefen R, Pryhuber GS, et al. (2009) G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development. Circulation. 119: 1524-32
Hoefen RJ, Berk BC. (2006) The multifunctional GIT family of proteins. Journal of Cell Science. 119: 1469-75
van Nieuw Amerongen GP, Natarajan K, Yin G, et al. (2004) GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. Circulation Research. 94: 1041-9
Berk BC, Min W, Yan C, et al. (2002) Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. Drug News & Perspectives. 15: 133-139
Hoefen RJ, Berk BC. (2002) The role of MAP kinases in endothelial activation. Vascular Pharmacology. 38: 271-3
Hojo Y, Saito Y, Tanimoto T, et al. (2002) Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism. Circulation Research. 91: 712-8
Surapisitchat J, Hoefen RJ, Pi X, et al. (2001) Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members. Proceedings of the National Academy of Sciences of the United States of America. 98: 6476-81
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