Holly C. Williams, Ph.D.

Affiliations: 
2012 Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Cell Biology, Molecular Biology, Pharmacology
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"Holly Williams"

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Kathy K. Griendling grad student 2012 Emory
 (Coronin 1B Regulates Platelet-derived Growth Factor-induced Migration and Reactive Oxygen Species Production.)
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Valdivia A, Duran C, Lee M, et al. (2023) Nox1-based NADPH oxidase regulates the Par protein complex activity to control cell polarization. Frontiers in Cell and Developmental Biology. 11: 1231489
Paredes F, Williams HC, Suster I, et al. (2022) Metabolic regulation of the proteasome under hypoxia by Poldip2 controls fibrotic signaling in vascular smooth muscle cells. Free Radical Biology & Medicine. 195: 283-297
Dolmatova EV, Forrester SJ, Wang K, et al. (2021) Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation. Cardiovascular Research
Paredes F, Williams HC, Quintana RA, et al. (2019) Mitochondrial Protein Poldip2 Controls VSMC Differentiated Phenotype by O-Linked GlcNAc Transferase-Dependent Inhibition of a Ubiquitin Proteasome System. Circulation Research
Luissint AC, Williams HC, Kim W, et al. (2019) Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice. Mucosal Immunology
Williams HC, Ma J, Weiss D, et al. (2018) The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo. Laboratory Investigation; a Journal of Technical Methods and Pathology
Paredes F, Lassègue B, Williams HC, et al. (2018) Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway. Proceedings of the National Academy of Sciences of the United States of America
Paredes F, Sheldon K, Lassègue B, et al. (2018) Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer. Proceedings of the National Academy of Sciences of the United States of America
Paredes F, Williams H, Martin AS. (2017) Poldip2 is an Oxygen-sensitive Mitochondrial Protein that Controls Oxidative/glycolytic Metabolism Balance and Proteasome Activity Free Radical Biology and Medicine. 112: 173-174
Martin-Garrido A, Williams HC, Lee M, et al. (2013) Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation. Plos One. 8: e79657
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