Navin R. Mahadevan, Ph.D.

Affiliations: 
2012 Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
Immunology, Cell Biology, Oncology
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"Navin Mahadevan"

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Maurizio Zanetti grad student 2012 UCSD
 (Cell-extrinsic effects of tumor endoplasmic reticulum stress on myeloid cells.)
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Publications

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Tani T, Mathsyaraja H, Campisi M, et al. (2024) TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity. Cancer Discovery
Li Y, Mahadevan NR, Duplaquet L, et al. (2023) Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1. Cell Reports. Medicine. 4: 101282
Gerton TJ, Green A, Campisi M, et al. (2023) Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells. Cancers. 15
Zhao W, Kepecs B, Mahadevan NR, et al. (2023) A cellular and spatial atlas of -associated tissue remodeling in lung adenocarcinoma. Biorxiv : the Preprint Server For Biology
Kitajima S, Tani T, Springer BF, et al. (2022) MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer. Cancer Cell
Sengupta S, Das S, Crespo AC, et al. (2022) Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes. Nature Cancer
Ricciuti B, Wang X, Alessi JV, et al. (2022) Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels. Jama Oncology
Knelson EH, Ivanova EV, Tarannum M, et al. (2022) Activation of tumor-cell STING primes NK-cell therapy. Cancer Immunology Research
Mahadevan NR, Knelson EH, Wolff JO, et al. (2021) Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity. Cancer Discovery
Sehgal K, Portell AJ, Ivanova EV, et al. (2020) Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade. The Journal of Clinical Investigation
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