Shilpa Sampathi, Ph.D.

Affiliations: 
2011 Molecular Biosciences Washington State University, Pullman, WA, United States 
Area:
Molecular Biology, Cell Biology, Genetics
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"Shilpa Sampathi"

Parents

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Weihang Chai grad student 2011 WSU
 (New Insights into the roles of DNA replication/repair proteins at telomeres.)
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Publications

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Sampathi S, Chernyavskaya Y, Haney MG, et al. (2022) Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia. Frontiers in Oncology. 12: 958673
Johnston G, Ramsey H, Liu Q, et al. (2020) Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia. Gene. 144758
Sampathi S, Acharya P, Zhao Y, et al. (2019) The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes. Nucleic Acids Research
Summers AR, Fischer MA, Stengel KR, et al. (2013) HDAC3 is essential for DNA replication in hematopoietic progenitor cells. The Journal of Clinical Investigation. 123: 3112-23
Lin W, Sampathi S, Dai H, et al. (2013) Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity. The Embo Journal. 32: 1425-39
Sampathi S, Chai W. (2011) Mapping the FEN1 interaction domain with hTERT. Biochemical and Biophysical Research Communications. 407: 34-8
Sampathi S, Chai W. (2011) Telomere replication: poised but puzzling. Journal of Cellular and Molecular Medicine. 15: 3-13
Dai X, Huang C, Bhusari A, et al. (2010) Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection. The Embo Journal. 29: 2788-801
Sampathi S, Bhusari A, Shen B, et al. (2009) Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance. The Journal of Biological Chemistry. 284: 3682-90
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