Karen Matsukuma, Ph.D.

Affiliations: 
2006 University of California, Irvine, Irvine, CA 
Area:
Molecular Biology
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"Karen Matsukuma"

Parents

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Timothy F. Osborne grad student 2006 UC Irvine
 (Nuclear receptor regulation of the fatty acid synthase promoter.)
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Publications

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Shain AH, Giacomini CP, Matsukuma K, et al. (2012) Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: E252-9
Shain AH, Matsukuma K, Giacomini C, et al. (2011) Abstract 3930: Integrative genomic analysis reveals SWI/SNF chromatin remodeling complex to be a TGFβ-mediating tumor suppressor pathway in pancreatic cancer Cancer Research. 71: 3930-3930
Matsukuma KE, Wang L, Bennett MK, et al. (2007) A key role for orphan nuclear receptor liver receptor homologue-1 in activation of fatty acid synthase promoter by liver X receptor. The Journal of Biological Chemistry. 282: 20164-71
Matsukuma KE, Bennett MK, Huang J, et al. (2006) Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase. Journal of Lipid Research. 47: 2754-61
Joseph SB, Laffitte BA, Patel PH, et al. (2002) Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. The Journal of Biological Chemistry. 277: 11019-25
Lawrence HJ, Rozenfeld S, Cruz C, et al. (1999) Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. Leukemia. 13: 1993-9
Goldkorn T, Balaban N, Matsukuma K, et al. (1998) EGF-Receptor phosphorylation and signaling are targeted by H2O2 redox stress. American Journal of Respiratory Cell and Molecular Biology. 19: 786-98
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