Mala Mani, Ph.D.
Affiliations: | 2006 | Johns Hopkins University, Baltimore, MD |
Area:
Molecular BiologyGoogle:
"Mala Mani"Parents
Sign in to add mentor| Srinivasan Chandrasegaran | grad student | 2006 | Johns Hopkins | |
| (Engineering and applications of zinc finger nucleases.) | ||||
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Publications
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| Gatt ME, Takada K, Mani M, et al. (2013) TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity. British Journal of Haematology. 162: 210-20 |
| Takada K, Zhu D, Bird GH, et al. (2012) Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Science Translational Medicine. 4: 148ra117 |
| Gatt ME, Zhao JJ, Ebert MS, et al. (2010) MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma. Blood |
| Görgün G, Calabrese E, Hideshima T, et al. (2010) A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma. Blood. 115: 5202-13 |
| Zhao J, Lin J, Chu Z, et al. (2010) Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway. Blood. 116: 1569-1569 |
| Mani M, Carrasco DE, Zhang Y, et al. (2009) BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. Cancer Research. 69: 7577-86 |
| Dutta-Simmons J, Zhang Y, Gorgun G, et al. (2009) Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Blood. 114: 2699-708 |
| Kandavelou K, Ramalingam S, London V, et al. (2009) Targeted manipulation of mammalian genomes using designed zinc finger nucleases. Biochemical and Biophysical Research Communications. 388: 56-61 |
| Gatt ME, Ebert M, Mani M, et al. (2009) The Functional Role of Microrna 15a/16-1 as Tumor Suppressor Genes in Multiple Myeloma. Blood. 114: 1963-1963 |
| Gatt ME, Mani M, Lerner M, et al. (2009) RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma. Blood. 114: 1786-1786 |