Nicole F. Villeneuve, Ph.D.
Affiliations: | 2011 | Pharmacology & Toxicology | University of Arizona, Tucson, AZ |
Area:
Molecular Biology, Pharmacology, ToxicologyGoogle:
"Nicole Villeneuve"Parents
Sign in to add mentor| Donna D. Zhang | grad student | 2011 | University of Arizona | |
| (Mechanistic study of USP15-dependent deubiquitination and characterization of natural compounds that modulate the Nrf2-Keap1 antioxidant response.) | ||||
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Publications
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| Villeneuve NF, Tian W, Wu T, et al. (2013) USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Molecular Cell. 51: 68-79 |
| Gosgnach W, Bourguignon M, Carpentier N, et al. (2012) GTPCH Serine81 phosphorylation modulates GTPCH–GFRP complex formation and GTPCH activity in aged endothelial cells under static and shear stress conditions Nitric Oxide. 27 |
| Ren D, Villeneuve NF, Jiang T, et al. (2011) Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 1433-8 |
| Wondrak GT, Villeneuve NF, Lamore SD, et al. (2010) The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules (Basel, Switzerland). 15: 3338-55 |
| Villeneuve NF, Lau A, Zhang DD. (2010) Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxidants & Redox Signaling. 13: 1699-712 |
| Lau A, Wang XJ, Zhao F, et al. (2010) A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Molecular and Cellular Biology. 30: 3275-85 |
| Villeneuve NF, Sun Z, Chen W, et al. (2009) Nrf2 and p21 regulate the fine balance between life and death by controlling ROS levels. Cell Cycle (Georgetown, Tex.). 8: 3255-6 |
| Lau A, Villeneuve NF, Sun Z, et al. (2008) Dual roles of Nrf2 in cancer Pharmacological Research. 58: 262-270 |
| Du Y, Villeneuve NF, Wang XJ, et al. (2008) Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. Environmental Health Perspectives. 116: 1154-61 |
| Wondrak GT, Cabello CM, Villeneuve NF, et al. (2008) Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress. Free Radical Biology & Medicine. 45: 385-95 |