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Maria E. De Obaldia, Ph.D.

Affiliations: 
2014 Immunology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Maria De Obaldia"
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Avinash Bhandoola grad student 2014 Penn
 (T-lineage specification and commitment requires constraint of myeloid gene expression programs by Hes1.)

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Publications

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De Obaldia ME, Bhandoola A. (2015) Transcriptional regulation of innate and adaptive lymphocyte lineages. Annual Review of Immunology. 33: 607-42
Rupp LJ, Brady BL, Carpenter AC, et al. (2014) The microRNA biogenesis machinery modulates lineage commitment during αβ T cell development. Journal of Immunology (Baltimore, Md. : 1950). 193: 4032-42
De Obaldia ME, Bell JJ, Wang X, et al. (2013) T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1. Nature Immunology. 14: 1277-84
Yang Q, Monticelli LA, Saenz SA, et al. (2013) T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity. 38: 694-704
De Obaldia ME, Bell JJ, Bhandoola A. (2013) Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus. Blood. 121: 64-71
Cai X, Gaudet JJ, Mangan JK, et al. (2011) Runx1 loss minimally impacts long-term hematopoietic stem cells. Plos One. 6: e28430
Chen MJ, Li Y, De Obaldia ME, et al. (2011) Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell. 9: 541-52
Zlotoff DA, Zhang SL, De Obaldia ME, et al. (2011) Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation. Blood. 118: 1962-70
Sultana DA, Bell JJ, Zlotoff DA, et al. (2010) Eliciting the T cell fate with Notch Seminars in Immunology. 22: 254-260
Melero-Martin JM, De Obaldia ME, Allen P, et al. (2010) Host myeloid cells are necessary for creating bioengineered human vascular networks in vivo. Tissue Engineering. Part A. 16: 2457-66
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