Francis C. Lynn, Ph.D.

Affiliations: 
2003 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Animal Physiology Biology, Molecular Biology, Pathology
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"Francis Lynn"

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Raymond A. Pederson grad student 2003 UBC
 (Regulation of glucose -dependent insulinotropic polypeptide (GIP) receptor expression in the pancreatic beta-cell.)
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Publications

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Kolic J, Sun WG, Cen HH, et al. (2024) Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Medrxiv : the Preprint Server For Health Sciences
Ellis CE, Mojibian M, Ida S, et al. (2023) Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-Versus-Host Disease. Transplantation
Sasaki S, Nian C, Xu EE, et al. (2023) Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5. Iscience. 26: 107311
Vanderkruk B, Maeshima N, Pasula DJ, et al. (2023) Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice. Diabetologia
Chu CMJ, Modi H, Ellis C, et al. (2022) Dynamic Ins2 Gene Activity Defines β-cell Maturity States. Diabetes
Ast J, Arvaniti A, Fine NHF, et al. (2020) Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications. 11: 467
Shomer N, Kadhim AZ, Grants JM, et al. (2019) Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans. Plos Genetics. 15: e1008508
Makkar G, Shrivastava V, Hlavay B, et al. (2019) Lrrc55 is a novel pro-survival factor in pancreatic islets. American Journal of Physiology. Endocrinology and Metabolism
Campbell SA, McDonald CL, Krentz NAJ, et al. (2019) TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation. Cell Reports. 28: 1830-1844.e6
Sabatini PV, Speckmann T, Lynn FC. (2018) Friend and foe: β-cell Ca signaling and the development of diabetes. Molecular Metabolism
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