Cornelia M. Smith, Ph.D.

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy, Molecular Biology, Cell Biology
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"Cornelia Smith"

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Edward L. LeCluyse grad student 2005 UNC Chapel Hill
 (Regulation of UDP -glucuronosyltransferase 1A1 gene expression in primary human hepatocytes.)
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Publications

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Smith CM, Nolan CK, Edwards MA, et al. (2012) A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes. Journal of Pharmaceutical Sciences. 101: 3989-4002
Rotroff DM, Wetmore BA, Dix DJ, et al. (2010) Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58
Faucette SR, Sueyoshi T, Smith CM, et al. (2006) Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. The Journal of Pharmacology and Experimental Therapeutics. 317: 1200-9
Smith CM, Graham RA, Krol WL, et al. (2005) Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells. The Journal of Pharmacology and Experimental Therapeutics. 315: 1256-64
Smith CM, Faucette SR, Wang H, et al. (2005) Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers. Journal of Biochemical and Molecular Toxicology. 19: 96-108
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