Eleanor E. Patton, Ph.D.

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Molecular Biology
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"Eleanor Patton"

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Mike Tyers grad student 2001 University of Toronto
 (E3 ubiquitin protein ligase complexes that regulate G1 phase in budding yeast.)
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Publications

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Zhou L, Ishizaki H, Spitzer M, et al. (2012) ALDH2 mediates 5-nitrofuran activity in multiple species. Chemistry & Biology. 19: 883-92
Ishizaki H, Spitzer M, Wildenhain J, et al. (2010) Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Disease Models & Mechanisms. 3: 639-51
Patton EE, Peyraud C, Rouillon A, et al. (2000) SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition. The Embo Journal. 19: 1613-24
Rouillon A, Barbey R, Patton EE, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. The Embo Journal. 19: 282-94
Schneider BL, Patton EE, Lanker S, et al. (1998) Yeast G1 cyclins are unstable in G1 phase. Nature. 395: 86-9
Patton EE, Willems AR, Tyers M. (1998) Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Trends in Genetics : Tig. 14: 236-43
Patton EE, Willems AR, Sa D, et al. (1998) Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes & Development. 12: 692-705
Willems AR, Lanker S, Patton EE, et al. (1996) Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway. Cell. 86: 453-63
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