Heath D. Skinner, Ph.D.

Affiliations: 
2007 West Virginia University, Morgantown, WV, United States 
Area:
Oncology
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"Heath Skinner"

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Bing-Hua Jiang grad student 2007 West Virginia University
 (The regulation and role of hypoxia inducible factor-1 (HIF-1) in human cancer.)
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Publications

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Song S, Xie M, Scott AW, et al. (2017) A Novel YAP1 Inhibitor targets CSCs-enriched Radiation Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma. Molecular Cancer Therapeutics
Chen Q, Song S, Wei S, et al. (2015) ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer. Oncotarget
Honjo S, Ajani JA, Scott AW, et al. (2014) Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer. International Journal of Oncology. 45: 567-74
Zhou G, Wang J, Zhao M, et al. (2014) Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Molecular Cell. 54: 960-74
Jiang Y, Cukic B, Adjeroh DA, et al. (2009) An algorithm for identifying novel targets of transcription factor families: application to hypoxia-inducible factor 1 targets. Cancer Informatics. 7: 75-89
Zhong XS, Liu LZ, Skinner HD, et al. (2007) Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells. Biochemical and Biophysical Research Communications. 358: 92-8
Frankenberry KA, Skinner H, Somasundar P, et al. (2006) Leptin receptor expression and cell signaling in breast cancer International Journal of Oncology. 28: 985-993
Skinner HD, Zheng JZ, Fang J, et al. (2004) Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling. The Journal of Biological Chemistry. 279: 45643-51
Somasundar P, Frankenberry KA, Skinner H, et al. (2004) Prostate cancer cell proliferation is influenced by leptin. The Journal of Surgical Research. 118: 71-82
Skinner HD, Zhong XS, Gao N, et al. (2004) Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells. Molecular and Cellular Biochemistry. 255: 19-23
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