Brendon P. Ladd, Ph.D.

Affiliations: 
2012 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmacology
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"Brendon Ladd"

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Donna S. Shewach grad student 2012 University of Michigan
 (Exploring and Exploiting DNA Repair Mechanisms to Improve Suicide Gene Therapy with Ganciclovir.)
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Publications

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Black JC, Atabakhsh E, Kim J, et al. (2015) Hypoxia drives transient site-specific copy gain and drug-resistant gene expression. Genes & Development. 29: 1018-31
Ladd B, Ackroyd JJ, Hicks JK, et al. (2013) Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity. Dna Repair. 12: 1114-21
Ladd B, O'Konek JJ, Ostruszka LJ, et al. (2011) Unrepairable DNA double-strand breaks initiate cytotoxicity with HSV-TK/ganciclovir. Cancer Gene Therapy. 18: 751-9
Ladd B, Shewach DS. (2011) Abstract 5374: Synergistic tumor cell killing with ganciclovir and vorinostat is due to inhibition of homologous recombination Cancer Research. 71: 5374-5374
O'Konek JJ, Ladd B, Flanagan SA, et al. (2010) Alteration of the carbohydrate for deoxyguanosine analogs markedly changes DNA replication fidelity, cell cycle progression and cytotoxicity. Mutation Research. 684: 1-10
Im MM, Flanagan SA, Ladd BP, et al. (2010) Abstract 1316: Late-occurring DNA damage is responsible for radiosensitization with gemcitabine Cancer Research. 70: 1316-1316
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