Akanksha Gupta, Ph.D.
Affiliations: | 2005 | North Dakota State University, Fargo, ND, United States |
Area:
Pharmacology, Molecular BiologyGoogle:
"Akanksha Gupta"Parents
Sign in to add mentor| Avadhesh C. Sharma | grad student | 2005 | North Dakota State University | |
| (Metalloprotease and endothelin -mediated signaling mechanisms in sepsis and related cardiovascular disorders.) | ||||
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Publications
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| Bouchard J, Malhotra R, Shah S, et al. (2015) Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study. Plos One. 10: e0120770 |
| Feingold KR, Grunfeld C, Heuer JG, et al. (2012) FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis. Endocrinology. 153: 2689-700 |
| Rajashekhar G, Gupta A, Marin A, et al. (2012) Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice. American Journal of Physiology. Renal Physiology. 302: F703-12 |
| Gupta A, Williams MD, Macias WL, et al. (2009) Activated protein C and acute kidney injury: Selective targeting of PAR-1. Current Drug Targets. 10: 1212-26 |
| Sharfuddin AA, Sandoval RM, Berg DT, et al. (2009) Soluble thrombomodulin protects ischemic kidneys. Journal of the American Society of Nephrology : Jasn. 20: 524-34 |
| Gupta A, Gerlitz B, Richardson MA, et al. (2009) Distinct functions of activated protein C differentially attenuate acute kidney injury. Journal of the American Society of Nephrology : Jasn. 20: 267-77 |
| Richardson MA, Gupta A, O'Brien LA, et al. (2008) Treatment of sepsis-induced acquired protein C deficiency reverses Angiotensin-converting enzyme-2 inhibition and decreases pulmonary inflammatory response. The Journal of Pharmacology and Experimental Therapeutics. 325: 17-26 |
| O'Brien LA, Richardson MA, Berg DT, et al. (2008) The puzzling role of TRAIL in endothelial cell biology [2] Arteriosclerosis, Thrombosis, and Vascular Biology. 28 |
| O'Brien LA, Richardson MA, Mehrbod SF, et al. (2007) Activated protein C decreases tumor necrosis factor related apoptosis-inducing ligand by an EPCR- independent mechanism involving Egr-1/Erk-1/2 activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2634-41 |
| Berg DT, Gupta A, Richardson MA, et al. (2007) Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11. The Journal of Biological Chemistry. 282: 36837-44 |