Andrew M. Hau, Ph.D.

Affiliations: 
2013 Oregon State University, Corvallis, OR 
Area:
Pharmacology, Cell Biology, Molecular Biology
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"Andrew Hau"

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Jane E. Ishmael grad student 2013 Oregon State
 (Biological Characterization of Coibamide A, a Marine Natural Product from a Panamanian Cyanobacterium.)
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Publications

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Hau AM, Gupta S, Leivo MZ, et al. (2019) Dynamic Regulation of Caveolin-1 Phosphorylation and Caveolae Formation by mTORC2 in Bladder Cancer Cells. The American Journal of Pathology
Hau AM, Nakasaki M, Nakashima K, et al. (2017) Differential mTOR pathway profiles in bladder cancer cell line subtypes to predict sensitivity to mTOR inhibition. Urologic Oncology
Sahu D, Gupta S, Hau AM, et al. (2016) Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase. The American Journal of Pathology
Hau AM, Leivo MZ, Gilder AS, et al. (2016) mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cellular Signalling
Gupta S, Hau AM, Al-Ahmadie HA, et al. (2016) Transforming Growth Factor-β Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion. The American Journal of Pathology
Hau AM, Gilder A, Hu J, et al. (2016) uPAR and mTORC2 as coupled targets for therapeutics development in bladder cancer. Journal of Clinical Oncology. 34: 447-447
Serrill JD, Wan X, Hau AM, et al. (2015) Coibamide A, a natural lariat depsipeptide, inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts. Investigational New Drugs
Serrill JD, Tan M, Fotso S, et al. (2015) Apoptolidins A and C activate AMPK in metabolically sensitive cell types and are mechanistically distinct from oligomycin A Biochemical Pharmacology. 93: 251-265
Nabika R, Suyama TL, Hau AM, et al. (2015) Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A. Bioorganic & Medicinal Chemistry Letters. 25: 302-6
Sahu D, Gupta S, Hau AM, et al. (2015) Abstract 4712: Targeting the arginine-nitric oxide pathway to arrest development and progression of invasive bladder cancer Cancer Research. 75: 4712-4712
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