Rupa Ray, Ph.D.

2007 Duke University, Durham, NC 
Pharmacology, Parasitology Biology
"Rupa Ray"


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Timothy Arthur James Haystead grad student 2007 Duke (Chemistry Tree)
 (Quinone reductase 2: A novel target of the quinolines.)
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Gonzalez-Gronow M, Fiedler JL, Farias Gomez C, et al. (2017) Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains. Biochemical and Biophysical Research Communications
Gonzalez-Gronow M, Cuchacovich M, Francos R, et al. (2015) Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus. Journal of Neuroimmunology. 287: 1-8
Gonzalez-Gronow M, Gomez CF, de Ridder GG, et al. (2014) Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro. The Journal of Biological Chemistry. 289: 25166-76
Gonzalez-Gronow M, Ray R, Wang F, et al. (2013) The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface. The Journal of Biological Chemistry. 288: 498-509
Ridder GGd, Ray R, Pizzo SV. (2013) Abstract 5248: Tunneling nanotubes connect melanoma cells and mediate transfer of mitochondria and GRP78. Cancer Research. 73: 5248-5248
Ray R, Ridder Gd, Pizzo SV. (2013) Abstract 1247: Development of GRP78 scFv-Subtilase fusion proteins for sensitization of melanoma to chemotherapeutics. Cancer Research. 73: 1247-1247
Ray R, de Ridder GG, Eu JP, et al. (2012) The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling. The Journal of Biological Chemistry. 287: 32755-69
de Ridder GG, Ray R, Pizzo SV. (2012) A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. Melanoma Research. 22: 225-35
de Ridder G, Ray R, Misra UK, et al. (2011) Modulation of the unfolded protein response by GRP78 in prostate cancer. Methods in Enzymology. 489: 245-57
de Ridder GG, Gonzalez-Gronow M, Ray R, et al. (2011) Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma. Melanoma Research. 21: 35-43
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