Garret Guenther, Ph.D.

Affiliations: 
2011 Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Cell Biology, Oncology
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"Garret Guenther"

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Aimee Edinger grad student 2011 UC Irvine
 (Starving cancer cells to death through ceramide-induced nutrient transporter down-regulation.)
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Publications

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Zhao L, Jachimowicz L, Lei M, et al. (2019) Abstract 1626: Comparison of two flow cytometry detection methods of circulating tumor cells: Direct identification and EpCAM affinity based enrichment Cancer Research. 79: 1626-1626
Jachimowicz L, Chiavario A, Ye P, et al. (2019) Multifunctional Potency Assays for Cancer Immunotherapy: ACEA Biosciences describes new tools to quantify tumor cell killing enhanced by bispecific T-cell engagers Genetic Engineering & Biotechnology News. 39
Cerignoli F, Abassi YA, Lamarche BJ, et al. (2018) In vitro immunotherapy potency assays using real-time cell analysis. Plos One. 13: e0193498
Cerignoli F, Xi B, Guenther G, et al. (2018) Abstract 5715: Monitoring immune cells-mediated cytolysis through impedance technology allows kinetic analysis of reagent efficacy Immunology
Kim SM, Roy SG, Chen B, et al. (2016) Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways. The Journal of Clinical Investigation
Cerignoli F, Xi B, Guenther G, et al. (2016) Abstract B093: In vitro testing solid cancers immunotherapy protocols through impedance technology allows dynamic and label-free evaluation of immune response and reagent efficacy Cancer Immunology Research. 4
Guenther GG, Liu G, Ramirez MU, et al. (2014) Loss of TSC2 confers resistance to ceramide and nutrient deprivation Oncogene. 33: 1776-1787
Romero Rosales K, Peralta ER, Guenther GG, et al. (2009) Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis. Molecular Biology of the Cell. 20: 2831-40
Guenther GG, Edinger AL. (2009) A new take on ceramide: starving cells by cutting off the nutrient supply. Cell Cycle (Georgetown, Tex.). 8: 1122-6
Guenther GG, Peralta ER, Rosales KR, et al. (2008) Ceramide starves cells to death by downregulating nutrient transporter proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 17402-7
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