John Auchampach
Affiliations: | Medical College of Wisconsin, Milwaukee, WI, United States |
Area:
Molecular BiologyGoogle:
"John Auchampach"Children
Sign in to add trainee| Laura M. Kreckler | grad student | 2006 | Medical College of Wisconsin |
| Dharini van der Hoeven | grad student | 2009 | Medical College of Wisconsin |
| Jason E. Maas | grad student | 2010 | Medical College of Wisconsin |
Collaborators
Sign in to add collaborator| Kenneth A. Jacobson | collaborator | 2008- | Medical College of Wisconsin (Neurotree) |
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Publications
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| Fisher CL, Pavan M, Salmaso V, et al. (2024) Extrahelical binding site for a 1-imidazo[4,5-c]quinolin-4-amine A adenosine receptor positive allosteric modulator on helix 8 and distal portions of transmembrane domains 1 and 7. Molecular Pharmacology |
| Tosh DK, Fisher CL, Salmaso V, et al. (2023) First Potent Macrocyclic A Adenosine Receptor Agonists Reveal G-Protein and β-Arrestin2 Signaling Preferences. Acs Pharmacology & Translational Science. 6: 1288-1305 |
| Gao ZG, Auchampach JA, Jacobson KA. (2022) Species dependence of A adenosine receptor pharmacology and function. Purinergic Signalling. 1-28 |
| Fallot LB, Suresh RR, Fisher CL, et al. (2022) Structure-Activity Studies of 1-Imidazo[4,5-]quinolin-4-amine Derivatives as A Adenosine Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. 65: 15238-15262 |
| Fisher CL, Fallot LB, Wan TC, et al. (2022) Characterization of Dual-Acting A Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα and Gα Isoprotein Activation. Acs Pharmacology & Translational Science. 5: 625-641 |
| Tosh DK, Salmaso V, Campbell RG, et al. (2021) A adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity. European Journal of Medicinal Chemistry. 113983 |
| Tosh DK, Salmaso V, Rao H, et al. (2020) Direct Comparison of (N)-Methanocarba and Ribose-Containing 2-Arylalkynyladenosine Derivatives as A Receptor Agonists. Acs Medicinal Chemistry Letters. 11: 1935-1941 |
| Tosh DK, Salmaso V, Rao H, et al. (2020) Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A Adenosine Receptors: Affinity Enhancement by -(2-Phenylethyl) Substitution. Journal of Medicinal Chemistry |
| Wan TC, Tampo A, Kwok WM, et al. (2019) Ability of CP-532,903 to protect mouse hearts from ischemia/reperfusion injury is dependent on expression of A adenosine receptors in cardiomyoyctes. Biochemical Pharmacology |
| Tosh DK, Rao H, Bitant A, et al. (2019) Design and in Vivo Characterization of A Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series. Journal of Medicinal Chemistry |