Bradley E. Bernstein

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Molecular Biology, Bioinformatics Biology
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"Bradley E. Bernstein"

Parents

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Wilhelmus G.J. Hol grad student 1997 University of Washington - Seattle/ NIH (Chemistry Tree)
 (Crystallographic investigations of phosphoglycerate kinase from the causative agent of sleeping sickness.)
Eric Lander post-doc MIT (MathTree)
Stuart L. Schreiber post-doc Harvard (Chemistry Tree)

Children

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Vicky W. Zhou grad student 2012 Harvard
Brian B. Liau post-doc Harvard Medical School (Chemistry Tree)
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Publications

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Johnstone SE, Reyes A, Qi Y, et al. (2020) Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer. Cell
Moore JE, Purcaro MJ, et al. (2020) Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 583: 699-710
Snyder MP, Gingeras TR, et al. (2020) Perspectives on ENCODE. Nature. 583: 693-698
Kato S, Weng QY, Insco ML, et al. (2020) Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discovery
Flavahan WA, Drier Y, Johnstone SE, et al. (2019) Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs. Nature
Brumbaugh J, Kim IS, Ji F, et al. (2019) Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology
Anastas JN, Zee BM, Kalin JH, et al. (2019) Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell
Flavahan WA, Drier Y, Johnstone SE, et al. (2019) Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST. Nature
Tarjan DR, Flavahan WA, Bernstein BE. (2019) Epigenome editing strategies for the functional annotation of CTCF insulators. Nature Communications. 10: 4258
Cejas P, Drier Y, Dreijerink KMA, et al. (2019) Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nature Medicine
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