Bradley E. Bernstein

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Molecular Biology, Bioinformatics Biology
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"Bradley E. Bernstein"

Parents

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Wilhelmus G.J. Hol grad student 1997 University of Washington - Seattle/ NIH (Chemistry Tree)
 (Crystallographic investigations of phosphoglycerate kinase from the causative agent of sleeping sickness.)
Eric Lander post-doc MIT (MathTree)
Stuart L. Schreiber post-doc Harvard (Chemistry Tree)

Children

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Vicky W. Zhou grad student 2012 Harvard
Brian B. Liau post-doc Harvard Medical School (Chemistry Tree)
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Publications

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McBrayer SK, Mayers JR, DiNatale GJ, et al. (2018) Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell
Karaayvaz M, Cristea S, Gillespie SM, et al. (2018) Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq. Nature Communications. 9: 3588
Santos-Rosa H, Schneider R, Bernstein BE, et al. (2018) Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin. Molecular Cell. 70: 983
Filbin MG, Tirosh I, Hovestadt V, et al. (2018) Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335
Kleppe M, Koche R, Zou L, et al. (2018) Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell. 33: 785-787
Kleppe M, Koche R, Zou L, et al. (2017) Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell
Faber AC, Song KA, Niederst MJ, et al. (2017) Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Ryan RJH, Petrovic J, Rausch DM, et al. (2017) A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas. Cell Reports. 21: 784-797
Rao SSP, Huang SC, Glenn St Hilaire B, et al. (2017) Cohesin Loss Eliminates All Loop Domains. Cell. 171: 305-320.e24
Shah N, Wang P, Wongvipat J, et al. (2017) Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer. Elife. 6
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