Reuben J. Shaw

Biology University of California, San Diego, La Jolla, CA 
Molecular Biology
"Reuben Shaw"


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Tyler Jacks grad student 1994-1998 MIT


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Dana M. Gwinn grad student 2011 UCSD
Maria M. Mihaylova grad student 2012 UCSD
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Schmitt DL, Curtis SD, Lyons AC, et al. (2022) Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nature Communications. 13: 3856
Van Nostrand JL, Hellberg K, Luo EC, et al. (2020) AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. Genes & Development
Yoon H, Spinelli JB, Zaganjor E, et al. (2020) PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle. Cell Metabolism
Schmitt DL, Zhang J, Chen M, et al. (2020) Illuminating Spatiotemporal Regulation of AMPK with a Genetically Encoded Excitation‐Ratiometric Biosensor for AMPK The Faseb Journal. 34: 1-1
Garcia D, Mihaylova MM, Shaw RJ. (2020) AMPK: Central Regulator of Glucose and Lipid Metabolism and Target of Type 2 Diabetes Therapeutics Liver. 472-484
Stein BD, Calzolari D, Hellberg K, et al. (2019) Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Cell Reports. 29: 3331-3348.e7
Stein BD, Herzig S, Martínez-Bartolomé S, et al. (2019) Comparison of CRISPR Genomic Tagging and Endogenous Immunoprecipitation coupled with Quantitative Mass Spectrometry to Identify Dynamic AMPK alpha 2 Protein Interactions. Journal of Proteome Research
Rodón L, Svensson RU, Wiater E, et al. (2019) The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer. Science Advances. 5: eaaw6455
Hollstein PE, Eichner LJ, Brun SN, et al. (2019) The AMPK-related kinases SIK1 and SIK3 mediate key tumor suppressive effects of LKB1 in NSCLC. Cancer Discovery
Hishida T, Vazquez-Ferrer E, Hishida-Nozaki Y, et al. (2019) Mutations in foregut SOX2 cells induce efficient proliferation via CXCR2 pathway. Protein & Cell
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