Noelle M. Ochotny, Ph.D.
Affiliations: | 2013 | Dentistry | University of Toronto, Toronto, ON, Canada |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Noelle Ochotny"Parents
Sign in to add mentor| Morris F. Manolson | grad student | 2013 | University of Toronto | |
| (Role of the V-ATPase a3 subunit in osteoclast maturation and function.) | ||||
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| Ochotny N, Voronov I, Owen C, et al. (2013) The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy. Journal of Cellular Biochemistry. 114: 2823-33 |
| Voronov I, Ochotny N, Jaumouillé V, et al. (2013) The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 108-18 |
| Ochotny N, Flenniken AM, Owen C, et al. (2011) The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1484-93 |
| Serrano EM, Ricofort RD, Zuo J, et al. (2009) Regulation of vacuolar H(+)-ATPase in microglia by RANKL. Biochemical and Biophysical Research Communications. 389: 193-7 |
| Kartner N, Ochotny N, Yao Y, et al. (2008) The V-ATPase a3 subunit: Potential therapeutic target for osteoporosis Bone. 43 |
| Ochotny N, Van Vliet A, Chan N, et al. (2006) Effects of human a3 and a4 mutations that result in osteopetrosis and distal renal tubular acidosis on yeast V-ATPase expression and activity. The Journal of Biological Chemistry. 281: 26102-11 |