Ariel R. Topletz, Ph.D.
Affiliations: | 2013 | Pharmaceutics | University of Washington, Seattle, Seattle, WA |
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"Ariel Topletz"Parents
Sign in to add mentorNina Isoherranen | grad student | 2013 | University of Washington | |
(The Relative Importance of CYP26A1 and CYP26B1 in Mediating Retinoid Homeostasis: Studies on the Formation, Elimination and Biological Activity of All-trans-Retinoic Acid Metabolites.) |
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Topletz AR, Zhong G, Isoherranen N. (2019) Scaling in vitro activity of CYP3A7 suggests human fetal livers do not clear retinoic acid entering from maternal circulation. Scientific Reports. 9: 4620 |
Jing J, Petroff R, Shum S, et al. (2017) Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
Topletz AR, Tripathy S, Foti RS, et al. (2015) Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Molecular Pharmacology. 87: 430-41 |
Topletz AR, Dennison JB, Barbuch RJ, et al. (2013) The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1651-61 |
Topletz AR, Le HN, Lee N, et al. (2013) Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 312-9 |
Shimshoni JA, Roberts AG, Scian M, et al. (2012) Stereoselective formation and metabolism of 4-hydroxy-retinoic Acid enantiomers by cytochrome p450 enzymes. The Journal of Biological Chemistry. 287: 42223-32 |
Topletz AR, Thatcher JE, Zelter A, et al. (2012) Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases. Biochemical Pharmacology. 83: 149-63 |