Heath Smith, Ph.D.

Affiliations: 
2012 Cancer Biology University of Wisconsin, Madison, Madison, WI 
Area:
Oncology, Molecular Biology, Immunology
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"Heath Smith"

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Douglas G. McNeel grad student 2012 UW Madison
 (Evaluating the SSX family of cancer-testis antigens as immunological targets for the treatment of prostate cancer.)
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Publications

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Shen M, Smith HA, Wei Y, et al. (2021) Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nature Cancer. 3: 60-74
Rekoske BT, Smith HA, Olson BM, et al. (2015) PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization. Cancer Immunology Research
Smith HA, Rekoske BT, McNeel DG. (2014) DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8+ T-cell immune responses. Vaccine. 32: 1707-15
Rekoske B, Smith HA, McNeel DG. (2013) Epitope optimization of a DNA vaccine targeting SSX-2 leads to PD-1 upregulation on antigen-specific CD8 T cells and PD-L1 upregulation on tumor cells Journal For Immunotherapy of Cancer. 1
McNeel DG, Smith HA, Eickhoff JC, et al. (2012) Phase I trial of tremelimumab in combination with short-term androgen deprivation in patients with PSA-recurrent prostate cancer. Cancer Immunology, Immunotherapy : Cii. 61: 1137-47
Zabransky DJ, Smith HA, Thoburn CJ, et al. (2012) Lenalidomide modulates IL-8 and anti-prostate antibody levels in men with biochemically recurrent prostate cancer. The Prostate. 72: 487-98
Smith HA, McNeel DG. (2011) Vaccines targeting the cancer-testis antigen SSX-2 elicit HLA-A2 epitope-specific cytolytic T cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 569-80
Smith HA, Cronk RJ, Lang JM, et al. (2011) Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. Cancer Research. 71: 6785-95
Smith HA, Maricque BB, Eberhardt J, et al. (2011) IgG responses to tissue-associated antigens as biomarkers of immunological treatment efficacy. Journal of Biomedicine & Biotechnology. 2011: 454861
Smith HA, McNeel DG. (2010) The SSX family of cancer-testis antigens as target proteins for tumor therapy. Clinical & Developmental Immunology. 2010: 150591
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