Jay D. Kissel, Ph.D.

Affiliations: 
2007 Molecular, Cellular, and Developmental Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Virology Biology, Molecular Biology
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"Jay Kissel"

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Donald H. Burke grad student 2007 Indiana University (Chemistry Tree)
 (Target specificity and structural characterization of single-stranded DNA aptamer RT1t49, a broad inhibitor of HIV-1 reverse transcriptases.)
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Publications

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Kissel JD, Held DM, Hardy RW, et al. (2007) Active site binding and sequence requirements for inhibition of HIV-1 reverse transcriptase by the RT1 family of single-stranded DNA aptamers. Nucleic Acids Research. 35: 5039-50
Kissel JD, Held DM, Hardy RW, et al. (2007) Single-stranded DNA aptamer RT1t49 inhibits RT polymerase and RNase H functions of HIV type 1, HIV type 2, and SIVCPZ RTs. Aids Research and Human Retroviruses. 23: 699-708
Held DM, Kissel JD, Thacker SJ, et al. (2007) Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers. Journal of Virology. 81: 5375-84
Held DM, Kissel JD, Saran D, et al. (2006) Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication. The Journal of Biological Chemistry. 281: 25712-22
Held DM, Kissel JD, Patterson JT, et al. (2006) HIV-1 inactivation by nucleic acid aptamers. Frontiers in Bioscience : a Journal and Virtual Library. 11: 89-112
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