Stephen L. Lessnick, MD, PhD

2004-2015 Pediatrics, Oncological Sciences University of Utah, Salt Lake City, UT 
 2015- Department of Pediatrics and Center for Childhood Cancer and Blood Diseases The Ohio State University and Nationwide Children's Hospital 
Molecular Biology, Oncology, Human Development, Genetics, Pathology
"Stephen Lessnick"
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Bayanjargal A, Taslim C, Showpnil IA, et al. (2024) The DBD-4 helix of EWS::FLI is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma. Biorxiv : the Preprint Server For Biology
Showpnil IA, Selich-Anderson J, Taslim C, et al. (2022) EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma. Nucleic Acids Research
Shulman DS, Whittle SB, Surdez D, et al. (2022) An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma. Npj Precision Oncology. 6: 65
Boone MA, Taslim C, Crow JC, et al. (2021) Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins. Molecular Cancer Research : McR
Boone MA, Taslim C, Crow JC, et al. (2021) The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma. Oncogene
Theisen ER, Selich-Anderson J, Miller KR, et al. (2020) Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein. Epigenetics. 1-20
Showpnil IA, Miller KR, Taslim C, et al. (2020) Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis. Journal of Visualized Experiments : Jove
Luo W, Xu C, Phillips S, et al. (2020) Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma. Oncotarget. 11: 1691-1704
Patel PO, Pishas KI, Taslim C, et al. (2019) Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma. Oncotarget. 10: 3865-3878
Theisen ER, Miller KR, Showpnil IA, et al. (2019) Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis. Genes & Cancer. 10: 21-38
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