Samar A. Hegazy, Ph.D.

Affiliations: 
2012 Laboratory Medicine and Pathology University of Alberta, Edmonton, Alberta, Canada 
Area:
Oncology, Molecular Biology
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"Samar Hegazy"

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Raymond Lai grad student 2012 University of Alberta
 (The Role of Oncogenic Tyrosine Kinase NPM-ALK in Anaplastic Large Cell Lymphoma Pathobiology.)
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Publications

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Hegazy SA, Alshareef A, Gelebart P, et al. (2013) Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 25: 295-307
Hegazy SA, Alshareef A, Gelebart P, et al. (2013) Corrigendum to "Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma" [Cell. Signal. 2013; 25:295-307] Cellular Signalling. 25: 580
Mereniuk TR, Maranchuk RA, Schindler A, et al. (2012) Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1-depleted cancers. Cancer Research. 72: 5934-44
Gelebart P, Hegazy SA, Wang P, et al. (2012) Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma. Blood Cancer Journal. 2: e82
Wang P, Zhang JD, Wu F, et al. (2012) The expression and oncogenic effects of the embryonic stem cell marker SALL4 in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 24: 1955-63
Young LC, Bone KM, Wang P, et al. (2011) Fusion tyrosine kinase NPM-ALK deregulates MSH2 and suppresses DNA mismatch repair function: Novel insights into a potent oncoprotein American Journal of Pathology. 179: 411-421
Hegazy SA, Wang P, Anand M, et al. (2010) The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions Journal of Biological Chemistry. 285: 19813-19820
Dien Bard J, Gelebart P, Anand M, et al. (2009) IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma. The American Journal of Pathology. 175: 825-34
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