Supriya R. Kulkarni, Ph.D.

Affiliations: 
2012 Pharmaceutical Sciences University of Rhode Island, Providence, RI, United States 
Area:
Pharmacology, Molecular Biology, Toxicology
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"Supriya Kulkarni"

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Angela L. Slitt grad student 2012 University of Rhode Island
 (Nrf2 as a nutrient sensitive transcription factor.)
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Publications

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Morgan ET, Dempsey JL, Mimche SM, et al. (2018) Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Kulkarni SR, Soroka CJ, Hagey LR, et al. (2016) Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid fed mouse model of cholestasis. Hepatology (Baltimore, Md.)
Yalcin EB, Kulkarni SR, Slitt AL, et al. (2015) Bisphenol a sulfonation is impaired in metabolic and liver disease. Toxicology and Applied Pharmacology
Xu J, Donepudi AC, More VR, et al. (2015) Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice. Obesity (Silver Spring, Md.). 23: 335-44
Kulkarni SR, Donepudi AC, Xu J, et al. (2014) Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human. Antioxidants & Redox Signaling. 20: 15-30
Kulkarni SR, Xu J, Donepudi AC, et al. (2013) Effect of caloric restriction and AMPK activation on hepatic nuclear receptor, biotransformation enzyme, and transporter expression in lean and obese mice. Pharmaceutical Research. 30: 2232-47
Kulkarni SR, Armstrong LE, Slitt AL. (2013) Caloric restriction-mediated induction of lipid metabolism gene expression in liver is enhanced by Keap1-knockdown. Pharmaceutical Research. 30: 2221-31
Xu J, Kulkarni SR, Donepudi AC, et al. (2012) Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice. Diabetes. 61: 3208-18
Xu J, Kulkarni SR, Li L, et al. (2012) UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 259-66
Beilke LD, Besselsen DG, Cheng Q, et al. (2008) Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 196-204
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