Ajay C. Donepudi, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of Rhode Island, Providence, RI, United States 
Area:
Pharmacology
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"Ajay Donepudi"

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Angela L. Slitt grad student 2013 University of Rhode Island
 (Effect of metabolic disease and xenobiotic exposure on hepatic ATP-binding cassette (Abc) drug transporter expression.)
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Truong JK, Bennett AL, Klindt C, et al. (2022) Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury. Journal of Lipid Research. 100261
Donepudi AC, Lee Y, Lee JY, et al. (2021) Multidrug resistance-associated protein 4 (Mrp4) is a novel genetic factor in the pathogenesis of obesity and diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21304
Donepudi AC, Smith GJ, Aladelokun O, et al. (2020) Lack of multidrug-resistance associated protein 4 prolongs partial hepatectomy-induced hepatic steatosis. Toxicological Sciences : An Official Journal of the Society of Toxicology
Donepudi AC, Goedken MJ, Schuetz JD, et al. (2019) Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity. Toxicology Reports. 6: 841-849
Donepudi AC, Ferrell JM, Boehme S, et al. (2018) Deficiency of cholesterol 7α-hydroxylase in bile acid synthesis exacerbates alcohol-induced liver injury in mice. Hepatology Communications. 2: 99-112
Shimpi PC, More VR, Paranjpe M, et al. (2017) Hepatic Lipid Accumulation and Nrf2 Expression following Perinatal and Peripubertal Exposure to Bisphenol A in a Mouse Model of Nonalcoholic Liver Disease. Environmental Health Perspectives. 125: 087005
Chiang JY, Pathak P, Liu H, et al. (2017) Intestinal Farnesoid X Receptor and Takeda G Protein Couple Receptor 5 Signaling in Metabolic Regulation. Digestive Diseases (Basel, Switzerland). 35: 241-245
Donepudi AC, Boehme S, Li F, et al. (2016) G protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis. Hepatology (Baltimore, Md.)
Donepudi AC, Cheng Q, Lu ZJ, et al. (2016) Hepatic Transporter Expression in Metabolic Syndrome: Phenotype, serum metabolic hormones, and transcription factor expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Xu J, Donepudi AC, More VR, et al. (2015) Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice. Obesity (Silver Spring, Md.). 23: 335-44
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