Kaalak Reddy, Ph.D.
Affiliations: | 2014 | Molecular and Medical Genetics | University of Toronto, Toronto, ON, Canada |
Area:
Genetics, Molecular BiologyGoogle:
"Kaalak Reddy"Parents
Sign in to add mentor| Christopher E. Pearson | grad student | 2014 | University of Toronto | |
| (Analysis of the Formation, Binding and Processing of Alternative Nucleic Acid Structures in Disease-Associated Repeat Sequences.) | ||||
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Publications
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| Nowzari ZR, Hale M, Ellis J, et al. (2024) Mutation of two intronic nucleotides alters RNA structure and dynamics inhibiting MBNL1 and RBFOX1 regulated splicing of the Insulin Receptor. Biorxiv : the Preprint Server For Biology |
| Madhanagopal BR, Talbot H, Rodriguez A, et al. (2023) Unusual Structural Properties of Switchback DNA. Biorxiv : the Preprint Server For Biology |
| Schroader JH, Handley MT, Reddy K. (2023) Inosine triphosphate pyrophosphatase: A guardian of the cellular nucleotide pool and potential mediator of RNA function. Wiley Interdisciplinary Reviews. Rna. e1790 |
| Mishra SK, Hicks SM, Frias JA, et al. (2023) Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy. Biorxiv : the Preprint Server For Biology |
| Schroader JH, Jones LA, Meng R, et al. (2022) Disease-associated inosine misincorporation into RNA hinders translation. Nucleic Acids Research |
| Reddy K, Cleary JD, Berglund JA. (2020) Drug Screen Tugs at Common Thread for Repeat Disorders. Trends in Pharmacological Sciences |
| Reddy K, Jenquin JR, McConnell OL, et al. (2019) A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels. Proceedings of the National Academy of Sciences of the United States of America |
| Reddy K, Jenquin JR, Cleary JD, et al. (2019) Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules. International Journal of Molecular Sciences. 20 |
| Handley MT, Reddy K, Wills J, et al. (2019) ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy. Plos Genetics. 15: e1007605 |
| Moss CF, Dalla Rosa I, Hunt LE, et al. (2017) Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model. Nucleic Acids Research |