Olivia S. Long, Ph.D.
Affiliations: | 2011 | University of Pittsburgh, Pittsburgh, PA, United States |
Area:
Molecular Biology, GeneticsGoogle:
"Olivia Long"Parents
Sign in to add mentor| Gary Silverman | grad student | 2011 | University of Pittsburgh | |
| (Genetic modifiers that affect the accumulation of the mutant protein alpha-1 antitrypsin-Z.) | ||||
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Publications
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| Long OS, Benson JA, Kwak JH, et al. (2014) A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover. Human Molecular Genetics. 23: 5109-22 |
| O'Reilly LP, Long OS, Cobanoglu MC, et al. (2014) A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency. Human Molecular Genetics. 23: 5123-32 |
| Miedel MT, Graf NJ, Stephen KE, et al. (2012) A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans. Plos One. 7: e40145 |
| Long OS, Gosai SJ, Kwak JH, et al. (2011) Using Caenorhabditis elegans to study serpinopathies. Methods in Enzymology. 499: 259-81 |
| Gosai SJ, Kwak JH, Luke CJ, et al. (2010) Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z. Plos One. 5: e15460 |
| Silverman GA, Luke CJ, Bhatia SR, et al. (2009) Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans. Pediatric Research. 65: 10-8 |
| Luke CJ, Pak SC, Askew YS, et al. (2007) An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury. Cell. 130: 1108-19 |