Jenny K. Ngo, Ph.D.
Affiliations: | 2008 | Biology | University of Southern California, Los Angeles, CA, United States |
Area:
Molecular BiologyGoogle:
"Jenny Ngo"Parents
Sign in to add mentor| Kelvin Davies | grad student | 2008 | USC | |
| (The human Lon protease in mitochondrial stress protection and aging.) | ||||
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Publications
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| Ngo JK, Pomatto LC, Davies KJ. (2013) Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging. Redox Biology. 1: 258-64 |
| Koltai E, Hart N, Taylor AW, et al. (2012) Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 303: R127-34 |
| Ngo JK, Pomatto LC, Bota DA, et al. (2011) Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 66: 1178-85 |
| Grune T, Catalgol B, Licht A, et al. (2011) HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress. Free Radical Biology & Medicine. 51: 1355-64 |
| Ngo JK, Davies KJ. (2009) Mitochondrial Lon protease is a human stress protein. Free Radical Biology & Medicine. 46: 1042-8 |
| Ngo JK, Davies KJ. (2007) Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging. Annals of the New York Academy of Sciences. 1119: 78-87 |
| Bota DA, Ngo JK, Davies KJ. (2005) Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radical Biology & Medicine. 38: 665-77 |