Tyler Jacks

Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
"Tyler Jacks"


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Julien Sage grad student MIT
Bart O Williams grad student 1992-1996 MIT (Neurotree)
Leisa Johnson grad student 1993-1996 MIT
Shane Shih grad student 1992-1997 MIT
James Brugarolas grad student 1994-1998 MIT
Reuben J. Shaw grad student 1994-1998 MIT
Kay F. MacLeod post-doc 1993-1997 MIT
Marianna Nacht post-doc 1993-1997 MIT
Scott Lowe post-doc 1996-1997 MIT
George Mulligan post-doc 1994-1998 MIT
Laura Attardi post-doc 1994-1999 MIT (GenetiTree)
Karen M. Cichowski post-doc 1996-1999 MIT
David A. Tuveson post-doc 1996-2000 MIT (Chemistry Tree)
Kevin M. Haigis post-doc 2002-2007 MIT
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Pentinmikko N, Iqbal S, Mana M, et al. (2019) Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Nature
Hamza B, Ng SR, Prakadan SM, et al. (2019) Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. Proceedings of the National Academy of Sciences of the United States of America
Guimaraes PPG, Tan M, Tammela T, et al. (2018) Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. Journal of Controlled Release : Official Journal of the Controlled Release Society
Lo JH, Hao L, Muzumdar MD, et al. (2018) iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer. Molecular Cancer Therapeutics
Dayton TL, Gocheva V, Miller KM, et al. (2018) Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma. Cancer & Metabolism. 6: 6
Tao Z, Muzumdar MD, Detappe A, et al. (2018) Differences in Nanoparticle Uptake in Transplanted and Autochthonous Models of Pancreatic Cancer. Nano Letters
Roper J, Tammela T, Akkad A, et al. (2018) Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation. Nature Protocols. 13: 217-234
Chen PY, Muzumdar MD, Dorans KJ, et al. (2017) Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells. Cancer Research
Roper J, Tammela T, Cetinbas NM, et al. (2017) Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. 35: 1211
Muzumdar MD, Chen PY, Dorans KJ, et al. (2017) Survival of pancreatic cancer cells lacking KRAS function. Nature Communications. 8: 1090
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