Charles Brenner

University of Iowa, Iowa City, IA 
"Charles Brenner"
Cross-listing: Chemistry Tree


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Robert S. Fuller grad student 1988-1993 Stanford Medical School (Neurotree)
Gregory A. Petsko post-doc 1993-1996 Brandeis (Chemistry Tree)
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Zhang Q, Li Z, Li Q, et al. (2024) Control of NAD homeostasis by autophagic flux modulates mitochondrial and cardiac function. The Embo Journal
Heer CD, Sanderson DJ, Voth LS, et al. (2020) Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity. The Journal of Biological Chemistry
Nam TS, Park DR, Rah SY, et al. (2020) Interleukin-8 drives CD38 to form NAADP from NADP and NAAD in the endolysosomes to mobilize Ca and effect cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Heer CD, Sanderson DJ, Alhammad YMO, et al. (2020) Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity. Biorxiv : the Preprint Server For Biology
Levine DC, Hong H, Weidemann BJ, et al. (2020) NAD Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging. Molecular Cell
Fons NR, Sundaram RK, Breuer GA, et al. (2019) PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. Nature Communications. 10: 3790
Elhassan YS, Kluckova K, Fletcher RS, et al. (2019) Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Reports. 28: 1717-1728.e6
Lindsay K, Brenner C, Hockenbery D, et al. (2019) CBMT-30. TARGETING NICOTINAMIDE ADENINE DINUCLEOTIDE BIOSYNTHESIS IN CNS TUMORS Neuro-Oncology. 21: vi39-vi39
Liu HW, Smith CB, Schmidt MS, et al. (2018) Pharmacological bypass of NAD salvage pathway protects neurons from chemotherapy-induced degeneration. Proceedings of the National Academy of Sciences of the United States of America
Mitchell SJ, Bernier M, Aon MA, et al. (2018) Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. Cell Metabolism. 27: 667-676.e4
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