Pawel Bieganowski, PhD

Affiliations: 
Mossakowski Medical Research Center 
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"Pawel Bieganowski"
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Publications

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Guranowski A, Wojdy?a AM, Zimny J, et al. (2010) Dual activity of certain HIT-proteins: A. thaliana Hint4 and C. elegans DcpS act on adenosine 5'-phosphosulfate as hydrolases (forming AMP) and as phosphorylases (forming ADP). Febs Letters. 584: 93-8
Wojcik M, Seidle HF, Bieganowski P, et al. (2006) Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste. The Journal of Biological Chemistry. 281: 33395-402
Bieganowski P, Seidle HF, Wojcik M, et al. (2006) Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions. The Journal of Biological Chemistry. 281: 22439-45
Seidle HF, Bieganowski P, Brenner C. (2005) Disease-associated mutations inactivate AMP-lysine hydrolase activity of Aprataxin. The Journal of Biological Chemistry. 280: 20927-31
Chou TF, Bieganowski P, Shilinski K, et al. (2005) 31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions. The Journal of Biological Chemistry. 280: 15356-61
Parks KP, Seidle H, Wright N, et al. (2004) Altered specificity of Hint-W123Q supports a role for Hint inhibition by ASW in avian sex determination. Physiological Genomics. 20: 12-4
Clements PM, Breslin C, Deeks ED, et al. (2004) The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4. Dna Repair. 3: 1493-502
Bieganowski P, Shilinski K, Tsichlis PN, et al. (2004) Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance. The Journal of Biological Chemistry. 279: 44656-66
Bieganowski P, Brenner C. (2004) Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell. 117: 495-502
Bieganowski P, Brenner C. (2003) The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad. The Journal of Biological Chemistry. 278: 33056-9
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